Rubidium block and rubidium permeability of the inward rectifier of frog skeletal muscle fibres.
نویسندگان
چکیده
منابع مشابه
Effect of temperature on the inward rectifier and gramicidin A-induced channels in the membrane of frog skeletal muscle fibres.
The conductance of frog skeletal muscle fibres in isotonic K2SO4 solution has been measured. Experiments were carried out under current-clamp conditions using a double sucrose-gap technique. The potassium conductances of the inward rectifier and the gramicidin channel in the same muscle fibre were compared. Potassium conductance of the inward rectifier increased with the temperature, with a val...
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Unidirectional chloride effluxes from small bundles of muscle fibers were measured under equilibrium conditions. It was found that chloride effluxes are described by the constant field theory with a chloride permeability constant, P(cl), which is independent of the chloride concentration and the membrane potential. The value of P(cl) at neutral pH was found to be 5 x 10(-6) cm/sec. Chloride mov...
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The late after-potential that follows trains of impulses in frog muscle fibers is virtually absent when most of the intracellular potassium is replaced by rubidium and the muscle is immersed in rubidium-containing Ringer's fluid. Its amplitude is also reduced in freshly dissected, potassium-containing muscle fibers that are immersed directly in Rb-Ringer's fluid. These findings are discussed in...
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Transport of Tl+ and Rb+ in human and rat erythrocytes was investigated in the presence of ouabain. The chloride-dependent cotransport of Tl+, Rb+ and Na+ was precluded by replacement of Cl- by NO3-. The inward and outward rate constants for the residual fluxes of the cations were determined by measuring the transport of 204Tl and 86Rb in double label experiments. The rate of passive transport ...
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Using choline-methyl-C(14) as a tracer, it has been shown that choline(+) penetrates into the cells of resting frog skeletal muscle at a rate similar to that of Na(+), and that it escapes from these cells much more slowly than does Na(+). Some implications of these findings are discussed.
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ژورنال
عنوان ژورنال: The Journal of Physiology
سال: 1980
ISSN: 0022-3751
DOI: 10.1113/jphysiol.1980.sp013333